Bilateral neck paragangliomas

Bilateral neck paragangliomas.

Paragangliomas of the head and neck are rare neoplasms presented as cervical mass, generally bilateral, that arise from chemoreceptors located at the carotid bifurcation (carotid body tumors), along the vagus nerve (vagal paragangliomas), and in the jugular fossa and tympanic cavity (jugulotympanic paragangliomas). They are typically asymptomatic at the beginning, highly vascular, slow-growing ...

Bilateral carotid body paragangliomas.

E606 CMAJ, June 14, 2011, 183(9) © 2011 Canadian Medical Association or its licensors A42-year-old man presented with bilateral, nontender, nonmobile masses in his neck, which had been present for several months. Magnetic resonance imaging (MRI) (Figure 1A) and magnetic resonance angiography (MRA) (Figure 1B) showed bilateral, intensely enhancing lesions that caused splaying of external and int...

Malignant head/neck paragangliomas. Comparative study.

BACKGROUND The objective of this study was to report 11 cases of malignant head and neck paraganglioma and to compare their epidemiological, clinical, and genetic characteristics, their natural history and their treatment with those of a series of 131 benign paragangliomas. PATIENTS AND METHODS Retrospective analysis of 142 patients with head and neck paraganglioma managed between 2001 and 20...

Imaging of bilateral neck paragangliomas with 68Ga-DOTATATE positron-emission tomography/CT.

Genetics of hereditary head and neck paragangliomas.

BACKGROUND The purpose of this study was to give an overview on hereditary syndromes associated with head and neck paragangliomas (HNPGs). METHODS Our methods were the review and discussion of the pertinent literature. RESULTS About one third of all patients with HNPGs are carriers of germline mutations. Hereditary HNPGs have been described in association with mutations of 10 different gene...